Clodronate sodium

Clodronic acid disodium salt is the disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used (generally as the tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases. Among its listed roles, it functions as a bone density conservation agent. It is an organic sodium salt and a one-carbon compound. It is grouped under the following drug class(es): Bisphosphonates. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Ossiten, Loron and Mebonat. Its PubChem CID is 31195.