Clodronate disodium

Disodium clodronate tetrahydrate is the tetrahydrate of the disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases. Among its listed roles, it functions as a bone density conservation agent. It is grouped under the following drug class(es): Bisphosphonates. Its therapeutic use is listed as anti-osteoporosis agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Bonefos, Sodium clodronate hydrate and Clodronic acid disodium tetrahydrate. Its PubChem CID is 23724874.

CAS No 88416-50-6
Molecular Formula CH10Cl2Na2O10P2
Molecular Weight 360.91 g/mol
Synonyms disodium;[dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate;tetrahydrate

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