Combination of imipenem and cilastatin that is used to treat bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent. It is grouped under the following drug class(es): Carbapenems. The directory classifies it as a commercial API with a peptide source/manufacturing origin. Other names for this substance include Tienam 500, Tainem and Thienam. Its PubChem CID is 17756656.
Cilastatin, imipenem drug combination
| CAS No | 92309-29-0 |
|---|---|
| Molecular Formula | C28H43N5O9S2 |
| Molecular Weight | 657.8 g/mol |
| Synonyms | (Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid;(5R,6S)-3-[2-(aminomethylideneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid |
Zoho Contact Form
"*" indicates required fields
Frequently Asked Questions
Combination of imipenem and cilastatin that is used to treat bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent.
The listed CAS number is 92309-29-0.
The listed molecular formula is C28H43N5O9S2.
The listed molecular weight is 657.8 g/mol.
(Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid;(5R,6S)-3-[2-(aminomethylideneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid.
The source lists Tienam 500, Tainem and Thienam.