Chlorhexidine gluconate

Chlorhexidine Gluconate is the gluconate salt form of chlorhexidine, a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine gluconate is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine gluconate penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram positive bacteria are more negatively charged, they are more sensitive to this agent. It is grouped under the following drug class(es): Antiseptics and Biguanides. Its therapeutic use is listed as dermatologicals and wound-healing agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Peridex, Corsodyl, Bioscrub and Hibistat. Its PubChem CID is 9552081.