Cetrorelix is a synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-tyrosyl, N(5)-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast. Among its listed roles, it functions as a GnRH antagonist and an antineoplastic agent. It is grouped under the following drug class(es): Antineoplastic agents, Hormones, LHRH analogues and Peptides. The directory classifies it as a commercial API with a peptide source/manufacturing origin. Other names for this substance include Cetrotide (TN) and Cetrorelixum. Its PubChem CID is 25074887.
Cetrorelix
| CAS No | 120287-85-6 |
|---|---|
| Molecular Formula | C70H92ClN17O14 |
| Molecular Weight | 1431.64 g/mol |
| Synonyms | (2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide |
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Frequently Asked Questions
Cetrorelix is a synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-tyrosyl, N(5)-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence.
The listed CAS number is 120287-85-6.
The listed molecular formula is C70H92ClN17O14.
The listed molecular weight is 1431.64 g/mol.
The source lists Cetrotide (TN) and Cetrorelixum.
It is listed under Antineoplastic agents, Hormones, LHRH analogues and Peptides.