Cerivastatin

Cerivastatin is (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity. It belongs to the class of pyridines, a dihydroxy monocarboxylic acid and a statin (synthetic). It is the conjugate acid of cerivastatin(1-). It is grouped under the following drug class(es): Cholesterol-reducing agents and Statins. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Cerivastatina and cerivastatin acid. Its PubChem CID is 446156.