Cephradine Monohydrate is the monohydrate form of cephradine, a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephradine monohydrate binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Its therapeutic use is listed as antibacterials. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Forticef and Cephradine (monohydrate). Its PubChem CID is 21124775.
Cephradine monohydrate
| CAS No | 31828-50-9 |
|---|---|
| Molecular Formula | C16H21N3O5S |
| Molecular Weight | 367.4 g/mol |
| Synonyms | (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate |
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Frequently Asked Questions
Cephradine Monohydrate is the monohydrate form of cephradine, a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephradine monohydrate binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.
The listed CAS number is 31828-50-9.
The listed molecular formula is C16H21N3O5S.
The listed molecular weight is 367.4 g/mol.
(6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate.
The source lists Forticef and Cephradine (monohydrate).