Cabergoline is an N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D2 receptor agonist, cabergoline is used in the management of Parkinson’s disease and of disorders associated with hyperprolactinaemia. Among its listed roles, it functions as a dopamine agonist, an antiparkinson drug and an antineoplastic agent. It is grouped under the following drug class(es): Dopamine agents, Fertility agents and Neurotransmitter agents. Its therapeutic use is listed as antiparkinsonian agents. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Velactis, Caberlin and Dostinex. Its PubChem CID is 54746.
Cabergoline
| CAS No | 81409-90-7 |
|---|---|
| Molecular Formula | C26H37N5O2 |
| Molecular Weight | 451.6 g/mol |
| Synonyms | (6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide |
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Frequently Asked Questions
Cabergoline is an N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group.
The listed CAS number is 81409-90-7.
The listed molecular formula is C26H37N5O2.
The listed molecular weight is 451.6 g/mol.
(6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide.
The source lists Velactis, Caberlin and Dostinex.