Butorphanol

Butorphanol is levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain. Among its listed roles, it functions as a opioid analgesic, an antitussive, a mu-opioid receptor agonist and a kappa-opioid receptor agonist. Butorphanol is a DEA Schedule IV controlled substance. Substances in the DEA Schedule IV have a low potential for abuse relative to substances in Schedule III. It is a Other substances substance. It is grouped under the following drug class(es): Schedule IV controlled substances. Its therapeutic use is listed as analgesics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Butorfanol and (-)-butorphanol. It is listed as a controlled drug substance (Schedule IV). Its PubChem CID is 5361092.