Bucillamine is an orally bioavailable derivative of the endogenous amino acid cysteine with two donatable thiol groups, with potential antioxidant and anti-inflammatory activities. Upon oral administration, bucillamine enters cells rapidly via the same pathway as cysteine and replenishes the thiol group in glutathione (GSH), thereby increasing intracellular GSH levels and GSH activity. Its therapeutic use is listed as anti-inflammatories and antirheumatic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Rimatil, Tiobutarit and Thiobutarit. Its PubChem CID is 656604.
Bucillamine
| CAS No | 65002-17-7 |
|---|---|
| Molecular Formula | C7H13NO3S2 |
| Molecular Weight | 223.3 g/mol |
| Synonyms | (2R)-2-[(2-methyl-2-sulfanylpropanoyl)amino]-3-sulfanylpropanoic acid |
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Frequently Asked Questions
Bucillamine is an orally bioavailable derivative of the endogenous amino acid cysteine with two donatable thiol groups, with potential antioxidant and anti-inflammatory activities.
The listed CAS number is 65002-17-7.
The listed molecular formula is C7H13NO3S2.
The listed molecular weight is 223.3 g/mol.
(2R)-2-[(2-methyl-2-sulfanylpropanoyl)amino]-3-sulfanylpropanoic acid.
The source lists Rimatil, Tiobutarit and Thiobutarit.