Beraprost

Beraprost is an organic heterotricyclic compound that is (3aS,8bS)-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan in which the hydrogens at positions 1R, 2R and 5 are replaced by (3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl, hydroxy and 3-carboxypropyl groups, respectively. It is a prostaglandin receptor agonist that is approved to treat pulmonary arterial hypertension in Asia. Among its listed roles, it functions as a vasodilator agent, a platelet aggregation inhibitor, an antihypertensive agent, a prostaglandin receptor agonist and an anti-inflammatory agent. It is a monocarboxylic acid, an organic heterotricyclic compound, a secondary alcohol, a secondary allylic alcohol and an enyne. It is the conjugate acid of beraprost(1-). It is grouped under the following drug class(es): Antithrombotic agents, Prostaglandins and Vasodilating agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Beraprostum and TRK-100STP FREE ACID. Its PubChem CID is 6917951.

CAS No 88430-50-6
Molecular Formula C24H30O5
Molecular Weight 398.5 g/mol
Synonyms 4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoic acid

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