Apremilast

Apremilast is a member of the class of isoindoles that is isoindole-1,3-dione substituted at position 4 by an acetamido group and at position 1 by a 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl group. Used for treatment of psoriatic arthritis. Among its listed roles, it functions as a phosphodiesterase IV inhibitor and a non-steroidal anti-inflammatory drug. It is an aromatic ether, a N-acetylarylamine, a sulfone and a member of phthalimides. It is grouped under the following drug class(es): Immunosuppressants, PDE4 inhibitors and Sulfones. Its therapeutic use is listed as anti-inflammatories and anti-psoriatic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include apremilastum, OTEZLA and CC-10004. Its PubChem CID is 11561674.

CAS No 608141-41-9
Molecular Formula C22H24N2O7S
Molecular Weight 460.5 g/mol
Synonyms N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide

Frequently Asked Questions