Apomorphine hydrochloride

Apomorphine Hydrochloride is the hydrochloride salt form of apomorphine, a derivative of morphine and non-ergoline dopamine agonist with high selectivity for dopamine D2, D3, D4 and D5 receptors. Apomorphine hydrochloride acts by stimulating dopamine receptors in the nigrostriatal system, hypothalamus, limbic system, pituitary gland, and blood vessels. This enhances motor function, suppresses prolactin release, and causes vasodilation and behavioral effects. Apomorphine hydrochloride is used to treat Parkinson’s disease and erectile dysfunction. Additionally, apomorphine hydrochloride acts on the chemoreceptor trigger zone and is used as a central emetic in the treatment of drug overdose. It is grouped under the following drug class(es): Dopamine agents and Neurotransmitter agents. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Taluvian, Apokyn, Uprima and Apmorphine hydrochloride hemihydrate. Its PubChem CID is 107882.

CAS No 41372-20-7
Molecular Formula C34H38Cl2N2O5
Molecular Weight 625.6 g/mol
Synonyms bis((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol);hydrate;dihydrochloride

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