Amphotericin B

Amphotericin B is a macrolide antibiotic used to treat potentially life-threatening fungal infections. Among its listed roles, it functions as a antiprotozoal drug, a bacterial metabolite and an antiamoebic agent. It is a macrolide antibiotic, a polyene antibiotic and an antibiotic antifungal drug. Amphotericin B is an antifungal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of several types of fungal infections, including histoplasmosis and cryptococcosis. Amphotericin B is also FDA-approved for the treatment of leishmaniasis, that is a parasitic infection. The FDA-approved uses for amphotericin B vary depending on the formulation of the drug. Many of the infections for which amphotericin B treatment is FDA-approved can be opportunistic infections (OIs) of HIV. It is grouped under the following drug class(es): Leishmaniasis agents. Its therapeutic use is listed as anti-infectives, antibiotics, antifungals, antiparasitics, antiprotozoals, dermatologicals and ophthalmic agents. The directory classifies it as a commercial API with a fermentation-derived source/manufacturing origin. Other names for this substance include Fungizone, Halizon, Ambil and Fungilin. Its PubChem CID is 5280965.