Amodiaquine

Amodiaquine is a quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position. Among its listed roles, it functions as a antimalarial, a non-steroidal anti-inflammatory drug, a drug allergen, a prodrug, an EC 2.1.1.8 (histamine N-methyltransferase) inhibitor and an anticoronaviral agent. It belongs to the class of phenols, an aminoquinoline, a secondary amino compound, a tertiary amino compound and an organochlorine compound. It is the conjugate base of amodiaquine(1+). Amodiaquine is an aminoquinoline used for the therapy of malaria. Amodiaquine has been linked to severe cases of acute hepatitis which can be fatal, for which reason it is recommended for use only as treatment and not for prophylaxis against malaria. Its therapeutic use is listed as anti-infectives, antimalarials and antiparasitics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Flavoquine, Camoquin, Camoquinal and Miaquin. Its PubChem CID is 2165.