Aclidinium

Aclidinium is a long-acting muscarinic antagonist used in the management of chronic obstructive pulmonary disease (COPD). It helps to relax airway muscles, improving breathing. Aclidinium is a carboxylic ester obtained by formal condensation between the carboxy group of 2-hydroxy(di-2-thienyl)acetic acid and the hydroxy group of N-(3-phenoxypropyl)-3-quinuclidinol. Used as its bromide salt for the long-term maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD). Among its listed roles, it functions as a bronchodilator agent and a muscarinic antagonist. It is a quaternary ammonium ion, a carboxylic ester, a member of thiophenes and an aromatic ether. Functionally, it is related to 3-quinuclidinol. It is grouped under the following drug class(es): Anticholinergics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Tudorza Pressair, Eklira Genuair and Bretaris Genuair. Its PubChem CID is 11434515.

CAS No 727649-81-2
Molecular Formula C26H30NO4S2+
Molecular Weight 484.7 g/mol
Synonyms [(3R)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octan-3-yl] 2-hydroxy-2,2-dithiophen-2-ylacetate

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