Acemetacin is a carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used to treat rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation. Its activity is due to both acemetacin and its major metabolite, indometacin. Among its listed roles, it functions as a prodrug, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, a non-steroidal anti-inflammatory drug and a non-narcotic analgesic. It is a N-acylindole, a monocarboxylic acid, a carboxylic ester, an indol-3-yl carboxylic acid and a member of monochlorobenzenes. Functionally, it is related to indometacin. It is grouped under the following drug class(es): Non-Steroidal Anti-Inflammatory Drugs (NSAID). Its therapeutic use is listed as analgesics, anti-inflammatories and antirheumatic agents. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Rantudil, Emflex and Acemix. Its PubChem CID is 1981.
Acemetacin
| CAS No | 53164-05-9 |
|---|---|
| Molecular Formula | C21H18ClNO6 |
| Molecular Weight | 415.8 g/mol |
| Synonyms | 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid |
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Frequently Asked Questions
Acemetacin is a carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used to treat rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation.
The listed CAS number is 53164-05-9.
The listed molecular formula is C21H18ClNO6.
The listed molecular weight is 415.8 g/mol.
2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid.
The source lists Rantudil, Emflex and Acemix.