9-Cis-retinoic acid

9-cis-retinoic acid is a retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry. Among its listed roles, it functions as a antineoplastic agent, a retinoid X receptor agonist, a metabolite and a keratolytic drug. It is the conjugate acid of 9-cis-retinoate. An important regulator of gene expression during growth and development, and in neoplasms. It is grouped under the following drug class(es): Retinoids. Its therapeutic use is listed as dermatologicals. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Alitretinoin, Panrexin, Atragen, Effederm and Avitoin. Its PubChem CID is 449171.

CAS No 5300-03-8
Molecular Formula C20H28O2
Molecular Weight 300.4 g/mol
Synonyms (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid

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