18F-Fluoromisonidazole is a radiofluorinated 2-nitroimidazole derivate with hypoxia-specific tracer activity. Misonidazole is reduced under hypoxic conditions and in reduced form covalently binds to macromolecules in hypoxic cells. 18F (fluorine-18) radiofluorination of misonidazole to form 18F-fluoromisonidazole allows radioisotopic imaging of reduced misonidazole bound to macromolecules in hypoxic cells. The directory classifies it as a clinical API with a synthetic source/manufacturing origin. Other names for this substance include [18F] FMISO, Miso F-18 and Fluorine-18 Fluoromisonidazole. Its PubChem CID is 450173.
(18F)Fluoromisonidazole
| CAS No | 104613-87-8 |
|---|---|
| Molecular Formula | C6H8FN3O3 |
| Molecular Weight | 188.15 g/mol |
| Synonyms | 1-(18F)fluoro-3-(2-nitroimidazol-1-yl)propan-2-ol |
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Frequently Asked Questions
18F-Fluoromisonidazole is a radiofluorinated 2-nitroimidazole derivate with hypoxia-specific tracer activity. Misonidazole is reduced under hypoxic conditions and in reduced form covalently binds to macromolecules in hypoxic cells.
The listed CAS number is 104613-87-8.
The listed molecular formula is C6H8FN3O3.
The listed molecular weight is 188.15 g/mol.
1-(18F)fluoro-3-(2-nitroimidazol-1-yl)propan-2-ol.
The source lists [18F] FMISO, Miso F-18 and Fluorine-18 Fluoromisonidazole.