It reacts with 5′-bromo-1′-phenyl-[3′-bipyridin]-6′(1′H)-one in the presence of palladium/copper catalysts to form the central 2-cyanophenyl moiety of the drug. 2-(1,3,2-Dioxaborinan-2-yl)benzonitrile is a key boronic ester intermediate used in the Suzuki-Miyaura coupling reaction to synthesize Perampanel, an AMPA receptor antagonist for epilepsy.
2-(1,3,2-Dioxaborinan-2-yl)benzonitrile
| API Name | Perampanel |
|---|---|
| CAS No | 172732-52-4 |
| Molecular Formula | C10H10BNO2 |
| Molecular Weight | 187.00 g/mol |
| Synonyms | 2-(1,3,2-dioxaborinan-2-yl)benzonitrile |
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Frequently Asked Questions
It reacts with 5′-bromo-1′-phenyl-[3′-bipyridin]-6′(1′H)-one in the presence of palladium/copper catalysts to form the central 2-cyanophenyl moiety of the drug. 2-(1,3,2-Dioxaborinan-2-yl)benzonitrile is a key boronic ester intermediate used in the Suzuki-Miyaura coupling reaction to synthesize Perampanel, an AMPA receptor antagonist for epilepsy.
The CAS number of 2-(1,3,2-Dioxaborinan-2-yl)benzonitrile is 172732-52-4.
The molecular formula of 2-(1,3,2-Dioxaborinan-2-yl)benzonitrile is C10H10BNO2.
The listed molecular weight of 2-(1,3,2-Dioxaborinan-2-yl)benzonitrile is 187.00 g/mol.
2-(1,3,2-Dioxaborinan-2-yl)benzonitrile is listed as being used in connection with the following API: Perampanel.
The listed synonym or IUPAC name for 2-(1,3,2-Dioxaborinan-2-yl)benzonitrile is 2-(1,3,2-dioxaborinan-2-yl)benzonitrile.