It acts as a structural building block to construct the specific cyclopropane core of the API, typically produced through reduction and subsequent functionalization to form the final active ingredient, often starting from 1(S)-(3-fluorophenyl)-2(R)-(hydroxymethyl)cyclopropanecarbonitrile. (1S,5R)-1-(3-Fluorophenyl)-3-oxabicyclohexan-2-one is a key chiral intermediate employed to synthesize lemborexant, an orexin receptor antagonist.
1-(3-Fluorophenyl)-3-oxabicyclo(3.1.0)hexan-2-one, (1S,5R)
| API Name | Lemborexant |
|---|---|
| CAS No | 528587-70-4 |
| Molecular Formula | C11H9FO2 |
| Molecular Weight | 192.19 g/mol |
| Synonyms | (1S,5R)-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexan-2-one |
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Frequently Asked Questions
It acts as a structural building block to construct the specific cyclopropane core of the API, typically produced through reduction and subsequent functionalization to form the final active ingredient, often starting from 1(S)-(3-fluorophenyl)-2(R)-(hydroxymethyl)cyclopropanecarbonitrile. (1S,5R)-1-(3-Fluorophenyl)-3-oxabicyclohexan-2-one is a key chiral intermediate employed to synthesize lemborexant, an orexin receptor antagonist.
The CAS number of 1-(3-Fluorophenyl)-3-oxabicyclo(3.1.0)hexan-2-one, (1S,5R) is 528587-70-4.
The molecular formula of 1-(3-Fluorophenyl)-3-oxabicyclo(3.1.0)hexan-2-one, (1S,5R) is C11H9FO2.
The listed molecular weight of 1-(3-Fluorophenyl)-3-oxabicyclo(3.1.0)hexan-2-one, (1S,5R) is 192.19 g/mol.
1-(3-Fluorophenyl)-3-oxabicyclo(3.1.0)hexan-2-one, (1S,5R) is listed as being used in connection with the following API: Lemborexant.
The listed synonym or IUPAC name for 1-(3-Fluorophenyl)-3-oxabicyclo(3.1.0)hexan-2-one, (1S,5R) is (1S,5R)-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexan-2-one.