2-Amino-1,9-dihydro-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylene cyclopentyl)-6H-purine-6-one

It serves as a key intermediate in medicinal chemistry for the synthesis of antiviral or anticancer nucleoside analogues, in which the protected cyclopentyl moiety allows selective functionalization. 2-Amino-1,9-dihydro-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-6H-purine-6-one is a highly substituted purine nucleoside analogue.

API Name Entecavir
CAS No 142217-81-0
Molecular Formula C26H27N5O3
Molecular Weight 457.5 g/mol
Synonyms 2-amino-9-[(1S,3R,4S)-2-methylidene-4-phenylmethoxy-3-(phenylmethoxymethyl)cyclopentyl]-1H-purin-6-one

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