2(1H)-Pyrimidinone, hydrochloride (1:1)

In the synthetic pathway, 2(1H)-Pyrimidinone provides the pyrimidine core of Tipiracil. Through selective halogenation, substitution, and functional group transformations, it is elaborated into Tipiracil, which acts as a thymidine phosphorylase inhibitor. The hydrochloride salt form is used for stability and handling in synthesis. 2(1H)-Pyrimidinone, hydrochloride (1:1) is a key intermediate in the synthesis of the active pharmaceutical ingredient Tipiracil hydrochloride.