It serves as the amine component in a nucleophilic aromatic substitution or coupling reaction, forming the core structure of the drug. It is often produced via chiral synthesis or resolution, such as using transaminase enzymes to ensure the specific S-configuration. (S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine is a critical chiral intermediate in the synthesis of Pralsetinib.
(R)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine
| API Name | Pralsetinib |
|---|---|
| CAS No | 2054317-97-2 |
| Molecular Formula | C10H11FN4 |
| Molecular Weight | 206.22 g/mol |
| Synonyms | (1R)-1-[6-(4-fluoropyrazol-1-yl)-3-pyridinyl]ethanamine |
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Frequently Asked Questions
It serves as the amine component in a nucleophilic aromatic substitution or coupling reaction, forming the core structure of the drug. It is often produced via chiral synthesis or resolution, such as using transaminase enzymes to ensure the specific S-configuration. (S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine is a critical chiral intermediate in the synthesis of Pralsetinib.
The CAS number of (R)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine is 2054317-97-2.
The molecular formula of (R)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine is C10H11FN4.
The listed molecular weight of (R)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine is 206.22 g/mol.
(R)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine is listed as being used in connection with the following API: Pralsetinib.
The listed synonym or IUPAC name for (R)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine is (1R)-1-[6-(4-fluoropyrazol-1-yl)-3-pyridinyl]ethanamine.