The compound has a predicted density of about 1.41 g/cm³ and a predicted pKa of 0.3, and it is typically stored under inert atmosphere (nitrogen or argon) at 2–8°C to maintain stability. (2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide (CAS 1197953-49-3) is an off-white to light yellow solid pharmaceutical intermediate with the synthesis of ALK inhibitors such as Brigatinib, which are targeted cancer therapies.
(2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide
| API Name | Brigatinib |
|---|---|
| CAS No | 1197953-49-3 |
| Molecular Formula | C12H12Cl2N3OP |
| Molecular Weight | 316.12 g/mol |
| Synonyms | 2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine |
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Frequently Asked Questions
The compound has a predicted density of about 1.41 g/cm³ and a predicted pKa of 0.3, and it is typically stored under inert atmosphere (nitrogen or argon) at 2–8°C to maintain stability. (2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide (CAS 1197953-49-3) is an off-white to light yellow solid pharmaceutical intermediate with the synthesis of ALK inhibitors such as Brigatinib, which are targeted cancer therapies.
The CAS number of (2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide is 1197953-49-3.
The molecular formula of (2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide is C12H12Cl2N3OP.
The listed molecular weight of (2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide is 316.12 g/mol.
(2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide is listed as being used in connection with the following API: Brigatinib.
The listed synonym or IUPAC name for (2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide is 2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine.