It acts as a building block, featuring a protected alcohol and a phosphonium ylide (Wittig reagent) for carbon-carbon bond formation, making it vital for constructing key fragments of these cholesterol-lowering medications. This specific chemical, Methyl (3R)-3-(((1,1-dimethylethyl)dimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate, is mainly used in organic synthesis as a crucial intermediate for creating complex molecules, notably in the production of HMG-CoA reductase inhibitors like certain statins (e.g., Rosuvastatin), helping form pyrimidine or pyrrole rings in those drug structures.
Methyl (3R)-3-(((1,1-dimethylethyl)dimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate
| API Name | Rosuvastatin calcium |
|---|---|
| CAS No | 147118-35-2 |
| Molecular Formula | C31H39O4PSi |
| Molecular Weight | 534.7 g/mol |
| Synonyms | methyl (3R)-3-[tert-butyl(dimethyl)silyl]oxy-5-oxo-6-(triphenyl-λ5-phosphanylidene)hexanoate |
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Frequently Asked Questions
It acts as a building block, featuring a protected alcohol and a phosphonium ylide (Wittig reagent) for carbon-carbon bond formation, making it vital for constructing key fragments of these cholesterol-lowering medications. This specific chemical, Methyl (3R)-3-(((1,1-dimethylethyl)dimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate, is mainly used in organic synthesis as a crucial intermediate for creating complex molecules, notably in the production of HMG-CoA reductase inhibitors like certain statins (e.g., Rosuvastatin), helping form pyrimidine or pyrrole rings in those drug structures.
The CAS number of Methyl (3R)-3-(((1,1-dimethylethyl)dimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate is 147118-35-2.
The molecular formula of Methyl (3R)-3-(((1,1-dimethylethyl)dimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate is C31H39O4PSi.
The listed molecular weight of Methyl (3R)-3-(((1,1-dimethylethyl)dimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate is 534.7 g/mol.
Methyl (3R)-3-(((1,1-dimethylethyl)dimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate is listed as being used in connection with the following API: Rosuvastatin calcium.
The listed synonym or IUPAC name for Methyl (3R)-3-(((1,1-dimethylethyl)dimethylsilyl)oxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate is methyl (3R)-3-[tert-butyl(dimethyl)silyl]oxy-5-oxo-6-(triphenyl-λ5-phosphanylidene)hexanoate.