3-Methyl-1-(2-piperidinophenyl)-1-butylamine, (S)-, N-acetyl-L-glutamate

It acts as a stable, optically pure salt for the (S)-amine, which is condensed with 4-ethoxycarbonyl-3-ethoxyphenylacetic acid, followed by hydrolysis to yield the final API. (S)-3-Methyl-1-(2-piperidinophenyl)butylamine N-acetyl-L-glutamate is a key chiral intermediate employed to synthesize Repaglinide, an oral anti-diabetic drug.

API Name Repaglinide
CAS No 219921-94-5
Molecular Formula C23H37N3O5
Molecular Weight 435.6 g/mol
Synonyms (2S)-2-acetamidopentanedioic acid;(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butan-1-amine

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