(Methoxymethyl)triphenylphosphonium chloride

It functions as a precursor to a Wittig reagent that enables carbon–carbon double bond formation through an olefination reaction with a suitable carbonyl compound. This reaction helps build an important structural fragment required for the molecule. After this step, the product undergoes further chemical transformations such as reduction, substitution, or deprotection steps during the manufacturing process, ultimately leading to the formation of the final Active Pharmaceutical Ingredient. (Methoxymethyl)triphenylphosphonium chloride serves as a synthetic reagent in the preparation of Tofacitinib.

CAS No 4009-98-7
Molecular Formula C20H20OP+
Molecular Weight 307.3 g/mol
Synonyms methoxymethyl(triphenyl)phosphanium

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