Ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

It acts as a precursor that undergoes substitution at the 7-position with 3-hydroxyazetidine, followed by ester hydrolysis and salt formation with meglumine to produce the final antibiotic. Ethyl 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate is a key intermediate in the synthesis of Delafloxacin meglumine.

API Name Delafloxacin meglumine
CAS No 189279-51-4
Molecular Formula C17H10ClF4N3O3
Molecular Weight 415.7 g/mol
Synonyms ethyl 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6,7-difluoro-4-oxoquinoline-3-carboxylate

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