[3-(Hydroxymethyl)phenyl]boronic acid

This coupling connects the hydroxymethyl-substituted phenyl ring to the pyrimidine, setting up the structure for subsequent etherification and other reactions needed to complete the Pacritinib molecule. [3-(Hydroxymethyl)phenyl]boronic acid is a key building block in synthesizing Pacritinib, mainly used in a Suzuki-Miyaura coupling reaction with a pyrimidine derivative (like 2,4-dichloropyrimidine) to form a crucial intermediate, establishing the phenyl-pyrimidine core of the drug.

API Name Pacritinib
CAS No 87199-15-3
Molecular Formula C7H9BO3
Molecular Weight 151.96 g/mol
Synonyms [3-(hydroxymethyl)phenyl]boronic acid

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