It is converted into the chiral aldehyde, then into the epoxide (2-oxiranyl-6-fluorochroman) intermediate, which is ultimately coupled to form the active pharmaceutical ingredient. (2S)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid is a key chiral intermediate in the synthesis of Nebivolol, specifically used to introduce the desired stereochemistry for the S-enantiomer.
(2S)-6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-carboxylic acid
| API Name | Nebivolol |
|---|---|
| CAS No | 129101-36-6 |
| Molecular Formula | C10H9FO3 |
| Molecular Weight | 196.17 g/mol |
| Synonyms | (2S)-6-fluoro-3,4-dihydro-2H-chromene-2-carboxylic acid |
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Frequently Asked Questions
It is converted into the chiral aldehyde, then into the epoxide (2-oxiranyl-6-fluorochroman) intermediate, which is ultimately coupled to form the active pharmaceutical ingredient. (2S)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid is a key chiral intermediate in the synthesis of Nebivolol, specifically used to introduce the desired stereochemistry for the S-enantiomer.
The CAS number of (2S)-6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-carboxylic acid is 129101-36-6.
The molecular formula of (2S)-6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-carboxylic acid is C10H9FO3.
The listed molecular weight of (2S)-6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-carboxylic acid is 196.17 g/mol.
(2S)-6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-carboxylic acid is listed as being used in connection with the following API: Nebivolol.
The listed synonym or IUPAC name for (2S)-6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-carboxylic acid is (2S)-6-fluoro-3,4-dihydro-2H-chromene-2-carboxylic acid.