3-Chloropropionyl chloride

3-Chloropropionyl chloride is employed to synthesize Beclamide as an acylating agent that reacts with an amine precursor via nucleophilic acyl substitution to form the key amide bond of the drug; during this reaction, the 3-chloropropionyl group is incorporated into the molecule and HCl is released, typically neutralized by a base like pyridine to drive the reaction efficiently.

API Name Beclamide
CAS No 625-36-5
Molecular Formula C3H4Cl2O
Molecular Weight 126.97 g/mol
Synonyms 3-chloropropanoyl chloride

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