7,10-Di-O-trichloroethoxycarbonyl-10-deacetyl Baccatin III

It is often employed as a protected intermediate in the synthesis of paclitaxel and related taxanes, in which the trichloroethoxycarbonyl groups act as removable protecting groups. 7,10-Di-O-trichloroethoxycarbonyl-10-deacetyl Baccatin III is a semi-synthetic derivative of baccatin III, a taxane diterpenoid core used in anticancer drug development.

API Name Paclitaxel
CAS No 95603-44-4
Molecular Formula C35H38Cl6O14
Molecular Weight 895.4 g/mol
Synonyms [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,15-dihydroxy-10,14,17,17-tetramethyl-11-oxo-9,12-bis(2,2,2-trichloroethoxycarbonyloxy)-6-oxatetracyclo[ -Show More

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