3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoic Acid

It acts as a precursor for Roflumilast, a PDE4 inhibitor, and shows promise in lab studies for fibrosis by targeting TGF-β1 pathways. 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoic Acid (DGM) is used mainly as a crucial building block (intermediate) in synthesizing Roflumilast, a medicine for severe COPD, but research also shows it might be a potential treatment for pulmonary fibrosis by inhibiting EMT (Epithelial-Mesenchymal Transition).

API Name Roflumilast
CAS No 162401-62-9
Molecular Formula C12H12F2O4
Molecular Weight 258.22 g/mol
Synonyms 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid

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