Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate

Its thiophene structure with specific functional groups makes it a valuable building block (a versatile synthon) for creating other bioactive molecules in drug discovery and fine chemical manufacturing. Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate is used mainly as a key chemical intermediate in the synthesis of complex pharmaceuticals, most notably Relugolix, a GnRH receptor antagonist used to treat advanced prostate cancer.

API Name Relugolix
CAS No 174072-89-0
Molecular Formula C14H14N2O4S
Molecular Weight 306.34 g/mol
Synonyms ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate

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