1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) N-hexadecanoyl-L-glutamate

It acts as an acylation agent to attach a fatty acid chain to the peptide backbone. 1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) N-hexadecanoyl-L-glutamate (often abbreviated as Palm-Glu(OSu)-OtBu or Palmitoyl-Glu(OSu)-OtBu) is a crucial building block used in the chemical synthesis of Liraglutide, a long-acting GLP-1 receptor agonist.

API Name Liraglutide
CAS No 204521-63-1
Molecular Formula C29H50N2O7
Molecular Weight 538.7 g/mol
Synonyms 1-O-tert-butyl 5-O-(2,5-dioxopyrrolidin-1-yl) (2S)-2-(hexadecanoylamino)pentanedioate

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