This fragment is typically coupled with a peptide segment, followed by deprotection of the trityl group and final cyclization to form the macrocyclic framework. (S,E)-3-Hydroxy-7-(tritylthio)hept-4-enoic acid is a critical chiral building block in the total synthesis of Romidepsin, used to construct the sulfur-containing side chain.
(S,E)-3-Hydroxy-7-(tritylthio)hept-4-enoic acid
| API Name | Romidepsin |
|---|---|
| CAS No | 180973-24-4 |
| Molecular Formula | C26H26O3S |
| Molecular Weight | 418.5 g/mol |
| Synonyms | (E,3S)-3-hydroxy-7-tritylsulfanylhept-4-enoic acid |
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Frequently Asked Questions
This fragment is typically coupled with a peptide segment, followed by deprotection of the trityl group and final cyclization to form the macrocyclic framework. (S,E)-3-Hydroxy-7-(tritylthio)hept-4-enoic acid is a critical chiral building block in the total synthesis of Romidepsin, used to construct the sulfur-containing side chain.
The CAS number of (S,E)-3-Hydroxy-7-(tritylthio)hept-4-enoic acid is 180973-24-4.
The molecular formula of (S,E)-3-Hydroxy-7-(tritylthio)hept-4-enoic acid is C26H26O3S.
The listed molecular weight of (S,E)-3-Hydroxy-7-(tritylthio)hept-4-enoic acid is 418.5 g/mol.
(S,E)-3-Hydroxy-7-(tritylthio)hept-4-enoic acid is listed as being used in connection with the following API: Romidepsin.
The listed synonym or IUPAC name for (S,E)-3-Hydroxy-7-(tritylthio)hept-4-enoic acid is (E,3S)-3-hydroxy-7-tritylsulfanylhept-4-enoic acid.