(R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid

It is a key building block that helps create the dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin, which was the first DPP-4 inhibitor approved by the FDA for type 2 diabetes treatment. (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid is a crucial intermediate in the synthesis of sitagliptin, a drug used to treat type 2 diabetes.

API Name Sitagliptin
CAS No 486460-00-8
Molecular Formula C15H18F3NO4
Molecular Weight 333.30 g/mol
Synonyms (3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-(2,4,5-trifluorophenyl)butanoic acid

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