Sitagliptin enamine

Its chemical structure is distinguished by a (2Z)-3-amino-1-(5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)-2-buten-1-one framework. Sitagliptin enamine is a chemical intermediate in the synthesis of sitagliptin, an oral antidiabetic drug.

API Name Sitagliptin
CAS No 767340-03-4
Molecular Formula C16H13F6N5O
Molecular Weight 405.30 g/mol
Synonyms (Z)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one

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