It incorporates the chiral 1,2-diol and benzodioxane moiety along with the pyrrolidinylmethyl substituent, which are critical for the molecule’s glucosylceramide synthase inhibitory activity. This intermediate undergoes final functionalization, including salt formation with tartrate, to yield the active Eliglustat tartrate. Its stereochemistry and functional groups are essential for binding specificity and pharmacological potency. N-((1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl)octanamide is a key advanced intermediate in the synthesis of Eliglustat tartrate.
N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl)octanamide
| API Name | Eliglustat tartrate |
|---|---|
| CAS No | 491833-29-5 |
| Molecular Formula | C23H36N2O4 |
| Molecular Weight | 404.5 g/mol |
| Synonyms | N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide |
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Frequently Asked Questions
It incorporates the chiral 1,2-diol and benzodioxane moiety along with the pyrrolidinylmethyl substituent, which are critical for the molecule’s glucosylceramide synthase inhibitory activity. This intermediate undergoes final functionalization, including salt formation with tartrate, to yield the active Eliglustat tartrate. Its stereochemistry and functional groups are essential for binding specificity and pharmacological potency. N-((1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl)octanamide is a key advanced intermediate in the synthesis of Eliglustat tartrate.
The CAS number of N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl)octanamide is 491833-29-5.
The molecular formula of N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl)octanamide is C23H36N2O4.
The listed molecular weight of N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl)octanamide is 404.5 g/mol.
N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl)octanamide is listed as being used in connection with the following API: Eliglustat tartrate.
The listed synonym or IUPAC name for N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl)octanamide is N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide.