5-Methyl-2-((2-nitrophenyl)amino)-3-thiophenecarbonitrile

It serves as a precursor in a multi-step process, typically formed by reacting 2-amino-5-methylthiophene-3-carbonitrile with 2-fluoro-nitrobenzene. 5-Methyl-2-((2-nitrophenyl)amino)-3-thiophenecarbonitrile, often referred to as ROY, is a critical intermediate in the synthesis of the antipsychotic drug Olanzapine.

API Name Olanzapine
CAS No 138564-59-7
Molecular Formula C12H9N3O2S
Molecular Weight 259.29 g/mol
Synonyms 5-methyl-2-(2-nitroanilino)thiophene-3-carbonitrile

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