It undergoes deprotection (removal of the tert-butyloxycarbonyl group) to yield the final active pharmaceutical ingredient. 1,1-Dimethylethyl N-((3R)-1-(7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-2,6-dioxo-1H-purin-8-yl)-3-piperidinyl)carbamate, often known as N-Boc Linagliptin, is the penultimate intermediate in the synthesis of the antidiabetic drug linagliptin.
1,1-Dimethylethyl N-((3R)-1-(7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-2,6-dioxo-1H-purin-8-yl)-3-piperidinyl)carbamate
| API Name | Linagliptin |
|---|---|
| CAS No | 668273-75-4 |
| Molecular Formula | C30H36N8O4 |
| Molecular Weight | 572.7 g/mol |
| Synonyms | tert-butyl N-[(3R)-1-[7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,6-dioxopurin-8-yl]piperidin-3-yl]carbamate |
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Frequently Asked Questions
It undergoes deprotection (removal of the tert-butyloxycarbonyl group) to yield the final active pharmaceutical ingredient. 1,1-Dimethylethyl N-((3R)-1-(7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-2,6-dioxo-1H-purin-8-yl)-3-piperidinyl)carbamate, often known as N-Boc Linagliptin, is the penultimate intermediate in the synthesis of the antidiabetic drug linagliptin.
The CAS number of 1,1-Dimethylethyl N-((3R)-1-(7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-2,6-dioxo-1H-purin-8-yl)-3-piperidinyl)carbamate is 668273-75-4.
The molecular formula of 1,1-Dimethylethyl N-((3R)-1-(7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-2,6-dioxo-1H-purin-8-yl)-3-piperidinyl)carbamate is C30H36N8O4.
The listed molecular weight of 1,1-Dimethylethyl N-((3R)-1-(7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-2,6-dioxo-1H-purin-8-yl)-3-piperidinyl)carbamate is 572.7 g/mol.
1,1-Dimethylethyl N-((3R)-1-(7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-2,6-dioxo-1H-purin-8-yl)-3-piperidinyl)carbamate is listed as being used in connection with the following API: Linagliptin.
The listed synonym or IUPAC name for 1,1-Dimethylethyl N-((3R)-1-(7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-2,6-dioxo-1H-purin-8-yl)-3-piperidinyl)carbamate is tert-butyl N-[(3R)-1-[7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,6-dioxopurin-8-yl]piperidin-3-yl]carbamate.