(3R,4S,5S,6R)-2-(3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol

It contains the C-aryl glucoside core structure that is essential for Canagliflozin. During the synthesis, this intermediate undergoes further functional group transformations such as deprotection and modification of the methoxy/ hydroxyl groups, which ultimately lead to the formation of the final Canagliflozin API. It is therefore an important late-stage intermediate in the manufacturing route of Canagliflozin. (3R,4S,5S,6R)-2-(3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol is a key intermediate used in this process.