1-(2-ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole

It is typically coupled with methyl 2-(4-(2-(tosyloxy)ethyl)phenyl)-2-methylpropanoate to form the core structure of bilastine, followed by ester hydrolysis to produce the final API. 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole is a key intermediate in the synthesis of Bilastine, a second-generation H1-antihistamine.

API Name Bilastine
CAS No 110963-63-8
Molecular Formula C16H23N3O
Molecular Weight 273.37 g/mol
Synonyms 1-(2-ethoxyethyl)-2-piperidin-4-ylbenzimidazole

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