This key intermediate introduces the essential indole moiety, which is vital for the drug’s biological activity, making its efficient synthesis a focus for industrial production. 2-(2-Methyl-1H-indol-3-yl)ethanamine (also called 2-methyltryptamine) is a crucial building block for Panobinostat (LBH589) synthesis, acting as the indole core that is coupled with a cinnamic acid derivative, often via reductive amination, to form the final histone deacetylase (HDAC) inhibitor structure for cancer treatment.
2-Methyl-1H-indole-3-ethylamine
| API Name | Panobinostat |
|---|---|
| CAS No | 2731-06-8 |
| Molecular Formula | C11H14N2 |
| Molecular Weight | 174.24 g/mol |
| Synonyms | 2-(2-methyl-1H-indol-3-yl)ethanamine |
Zoho Contact Form - Pharma Intermediates
"*" indicates required fields
Frequently Asked Questions
This key intermediate introduces the essential indole moiety, which is vital for the drug's biological activity, making its efficient synthesis a focus for industrial production. 2-(2-Methyl-1H-indol-3-yl)ethanamine (also called 2-methyltryptamine) is a crucial building block for Panobinostat (LBH589) synthesis, acting as the indole core that is coupled with a cinnamic acid derivative, often via reductive amination, to form the final histone deacetylase (HDAC) inhibitor structure for cancer treatment.
The CAS number of 2-Methyl-1H-indole-3-ethylamine is 2731-06-8.
The molecular formula of 2-Methyl-1H-indole-3-ethylamine is C11H14N2.
The listed molecular weight of 2-Methyl-1H-indole-3-ethylamine is 174.24 g/mol.
2-Methyl-1H-indole-3-ethylamine is listed as being used in connection with the following API: Panobinostat.
The listed synonym or IUPAC name for 2-Methyl-1H-indole-3-ethylamine is 2-(2-methyl-1H-indol-3-yl)ethanamine.