It reacts via N-alkylation with 4-bromomethyl-2′-cyanobiphenyl, followed by N-acylation with valeryl chloride, tetrazole ring formation, and debenzylation to produce the antihypertensive drug. L-Valine benzyl ester hydrochloride is a crucial chiral intermediate employed to synthesize Valsartan to introduce the (S)-valine moiety.
L-Valine benzyl ester hydrochloride
| API Name | Valsartan |
|---|---|
| CAS No | 2462-34-2 |
| Molecular Formula | C12H18ClNO2 |
| Molecular Weight | 243.73 g/mol |
| Synonyms | benzyl (2S)-2-amino-3-methylbutanoate;hydrochloride |
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Frequently Asked Questions
It reacts via N-alkylation with 4-bromomethyl-2′-cyanobiphenyl, followed by N-acylation with valeryl chloride, tetrazole ring formation, and debenzylation to produce the antihypertensive drug. L-Valine benzyl ester hydrochloride is a crucial chiral intermediate employed to synthesize Valsartan to introduce the (S)-valine moiety.
The CAS number of L-Valine benzyl ester hydrochloride is 2462-34-2.
The molecular formula of L-Valine benzyl ester hydrochloride is C12H18ClNO2.
The listed molecular weight of L-Valine benzyl ester hydrochloride is 243.73 g/mol.
L-Valine benzyl ester hydrochloride is listed as being used in connection with the following API: Valsartan.
The listed synonym or IUPAC name for L-Valine benzyl ester hydrochloride is benzyl (2S)-2-amino-3-methylbutanoate;hydrochloride.