Octahydroindole-2-carboxylic acid

Octahydroindole-2-carboxylic acid (Oic) is a valuable chiral building block in medicinal chemistry, mainly used as a key intermediate for synthesizing powerful ACE inhibitors like Perindopril and Trandolapril (for hypertension/heart failure) and explored in designing other drugs, including opioid receptor modulators, anti-cancer agents, and peptide mimetics for pain management, leveraging its rigid structure to enhance drug stability and potency, with potential uses in specialized polymers, agrochemicals, and cosmetics too.

API Name Trandolapril
CAS No 80875-98-5
Molecular Formula C9H15NO2
Molecular Weight 169.22 g/mol
Synonyms 2,3,3a,4,5,6,7,7a-octahydro-1H-indole-2-carboxylic acid

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