It also serves as an analytical standard, a tracer (deuterated form), and a building block in organic synthesis for developing new targeted therapies and studying biological pathways. 4-(4-Aminophenoxy)-N-methylpicolinamide (APNMP) is used mainly as a key pharmaceutical intermediate in medicinal chemistry, especially for synthesizing anticancer drugs, notably sorafenib (Nexavar) and its structural analogs, by targeting protein kinases like Raf kinase and MET protein to inhibit cancer cell growth and proliferation.
4-(4-Aminophenoxy)-N-methylpicolinamide
| API Name | Sorafenib |
|---|---|
| CAS No | 284462-37-9 |
| Molecular Formula | C13H13N3O2 |
| Molecular Weight | 243.26 g/mol |
| Synonyms | 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide |
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