methyl 2-(chloromethyl)-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylate

It acts as the core building block in which the 2-chloromethyl group is substituted to connect the piperidine-pyridine side chain, while the 5-carboxylate is later hydrolyzed to the active carboxylic acid. Methyl 2-(chloromethyl)-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylate is a key advanced intermediate in the synthesis of Danuglipron, an oral GLP-1 receptor agonist.