5-(4-Methylpiperazin-1-yl)pyridin-2-amine

5-(4-Methylpiperazin-1-yl)pyridin-2-amine is a critical pharmaceutical intermediate employed to synthesize Trilaciclib (sold under the brand name Cosela), a CDK4/6 inhibitor designed to protect bone marrow from chemotherapy-induced damage.

API Name Trilaciclib
CAS No 571189-49-6
Molecular Formula C10H16N4
Molecular Weight 192.26 g/mol
Synonyms 5-(4-methylpiperazin-1-yl)pyridin-2-amine